الأحد، 12 يونيو 2011

Urine Creatinine - Spot Collection - Creatinine-Urine


Overview & Description

This test measures the amount of creatinine in the urine. Creatinine is produced in the muscles and filtered by the kidneys. The amount of creatinine in the urine is a measure of how well the kidneys are functioning.
Who is a candidate for the test?
This test may be ordered to check a person's intake of fluid or of high protein foods such as meat. It also detects muscle damage or degeneration, nerve damage from diabetes mellitus, or other disorders of the endocrine system. It provides clues about damage or blockages within the kidney, bladder or other parts of the urinary system.
How is the test performed?
Either a 24-hour urine sample or a spot sample may be done.
For a spot sample, the person urinates and collects a small sample in a container. The container is sealed and given to the healthcare provider.
For a 24-hour urine sample, the person should follow the specific instructions of the healthcare provider. In general, this schedule is followed:
  • Day 1: The person urinates upon arising without collecting that sample. After that, he or she collects all of his or her urine for the next 24 hours in a special container.

  • Day 2: First thing in the morning, the person urinates into the container again. Then the individual covers it and refrigerates it. The sample is brought to the doctor, who will send it to the lab for analysis.

    • Preparation & Expectations

    What is involved in preparation for the test?
    The person should request specific instructions from the doctor.

    Results and Values

    What do the test results mean?
    The healthy range for creatinine in urine is:
  • spot collection, 25 to 400 milligrams/deciliter (mg/dL)

  • 24-hour sample, 0 to 0.25 grams per 24 hours


    • Abnormal creatinine levels may suggest the following:
  • acromegaly, which is an overgrowth of bone caused by too much human growth hormone

  • acute tubular necrosis, which is the failure of the kidney that follows damage to its filtering tubes

  • dehydration, which results from inadequate fluid intake

  • diabetic nephropathy, which means damage to the small blood vessels of the kidney caused by diabetes mellitus

  • glomerulonephritis, which is an inflammation and scarring in the filtering system of the kidneys

  • muscular dystrophy, a congenital disorder causing muscle wasting

  • pyelonephritis, a bacterial infection of the kidneys

  • kidney failure

  • an obstruction of the kidneys, bladder, or tubes

  • myasthenia gravis, which is a nervous system disorder that causes progressive muscle weakness and fatigue

  • a diet high in meat

    • Attribution

    Author:David T. Moran, MD
    Date Written:
    Editor:Crist, Gayle P., MS, BA
    Edit Date:10/16/02
    Reviewer:Kathleen A. MacNaughton, RN, BSN
    Date Reviewed:10/16/02
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